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dc.contributor.author남상집-
dc.date.accessioned2016-08-28T10:08:54Z-
dc.date.available2016-08-28T10:08:54Z-
dc.date.issued2013-
dc.identifier.issn0163-3864-
dc.identifier.otherOAK-10044-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/223686-
dc.description.abstractTwo new cyclic hexapeptides, nocardiamides A (1) and B (2), were isolated from the culture broth of marine-derived actinomycete CNX037 strain that was identified as a Nocardiopsis species. The planar structures of nocardiamides A (1) and B (2) were assigned on the basis of 1D and 2D NMR and HRESIMS spectroscopic analyses. Their absolute configurations were deduced by the advanced Marfey's method and chiral-phase HPLC analysis. The challenge of locating two d- and one l-valine residue in 1 and 2 was accomplished by total synthesis using solid-phase peptide synthetic methods. Both 1 and 2 showed negligible antimicrobial activities against seven indicator strains and exhibited no cytotoxicity against HCT-116. © 2013 The American Chemical Society and American Society of Pharmacognosy.-
dc.languageEnglish-
dc.titleNocardiamides A and B, two cyclohexapeptides from the marine-derived actinomycete Nocardiopsis sp. CNX037-
dc.typeArticle-
dc.relation.issue4-
dc.relation.volume76-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage694-
dc.relation.lastpage701-
dc.relation.journaltitleJournal of Natural Products-
dc.identifier.doi10.1021/np400009a-
dc.identifier.wosidWOS:000318264700029-
dc.identifier.scopusid2-s2.0-84876889883-
dc.author.googleWu Z.-C.-
dc.author.googleLi S.-
dc.author.googleNam S.-J.-
dc.author.googleLiu Z.-
dc.author.googleZhang C.-
dc.contributor.scopusid남상집(36455982300)-
dc.date.modifydate20180104081001-
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자연과학대학 > 화학·나노과학전공 > Journal papers
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