DSpace at EWHA: Cytotoxic scalarane sesterterpenes from a Korean marine sponge Psammocinia sp.

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DSpace at EWHA자연과학대학 화학·나노과학전공 Journal papers

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DC Field	Value	Language
dc.contributor.author	남상집	*
dc.date.accessioned	2016-08-28T10:08:44Z	-
dc.date.available	2016-08-28T10:08:44Z	-
dc.date.issued	2013	*
dc.identifier.issn	0960-894X	*
dc.identifier.other	OAK-9943	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/223597	-
dc.description.abstract	Three novel scalarane sesterterpenes were isolated from a Korean marine sponge, Psammocinia sp., along with four known derivatives. Their structures were elucidated on the basis of NMR, MS and IR spectroscopic data. The three new compounds are 12-deacetoxy-23-hydroxyscalaradial (1), 12-dehydroxy-23- hydroxyhyrtiolide (2) and 12-O-acetyl-16-deacetoxy-23-acetoxyscalarafuran (3), respectively, and the four known compounds are 12-deacetoxy-23- hydroxyheteronemin (4), 12-deacetoxy-23-acetoxy-19-O-acetylscalarin (5), 12-deacetoxy-23-O-acetoxyheteronemin (6) and 12-deacetoxyscalaradial (7). They exhibited cytotoxicity against intractable human cancer cell lines A498, ACHN, MIA-paca and PANC-1, with an IC50 range of 0.4-48 μM. © 2013 Elsevier Ltd. All rights reserved.	*
dc.language	English	*
dc.title	Cytotoxic scalarane sesterterpenes from a Korean marine sponge Psammocinia sp.	*
dc.type	Article	*
dc.relation.issue	8	*
dc.relation.volume	23	*
dc.relation.index	SCI	*
dc.relation.index	SCIE	*
dc.relation.index	SCOPUS	*
dc.relation.startpage	2336	*
dc.relation.lastpage	2339	*
dc.relation.journaltitle	Bioorganic and Medicinal Chemistry Letters	*
dc.identifier.doi	10.1016/j.bmcl.2013.02.061	*
dc.identifier.wosid	WOS:000316934000012	*
dc.identifier.scopusid	2-s2.0-84875413625	*
dc.author.google	Hahn D.	*
dc.author.google	Won D.H.	*
dc.author.google	Mun B.	*
dc.author.google	Kim H.	*
dc.author.google	Han C.	*
dc.author.google	Wang W.	*
dc.author.google	Chun T.	*
dc.author.google	Park S.	*
dc.author.google	Yoon D.	*
dc.author.google	Choi H.	*
dc.author.google	Nam S.-J.	*
dc.author.google	Ekins M.	*
dc.author.google	Chin J.	*
dc.author.google	Kang H.	*
dc.contributor.scopusid	남상집(57208839798)	*
dc.date.modifydate	20240220120010	*