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Synthesis and antifungal evaluation of 7-arylamino-5,8-dioxo-5,8- dihydroisoquinoline-4-carboxylates

Title
Synthesis and antifungal evaluation of 7-arylamino-5,8-dioxo-5,8- dihydroisoquinoline-4-carboxylates
Authors
Ryu C.-K.Song A.L.Hong J.A.
Ewha Authors
유충규
SCOPUS Author ID
유충규scopus
Issue Date
2013
Journal Title
Bioorganic and Medicinal Chemistry Letters
ISSN
0960-894XJCR Link
Citation
vol. 23, no. 7, pp. 2065 - 2068
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
7-Arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Most of tested compounds showed good antifungal activity. The results suggest that those 5,8-dioxo-5,8-dihydroisoquinolines would be potent antifungal agents. © 2013 Elsevier Ltd. All rights reserved.
DOI
10.1016/j.bmcl.2013.01.130
Appears in Collections:
약학대학 > 약학과 > Journal papers
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