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Enhanced activities of reproductive system in male rat treated with male silkworm pupae extract

Title
Enhanced activities of reproductive system in male rat treated with male silkworm pupae extract
Authors
Kwon M.-G.Kim D.-S.Lee J.-H.Park S.-R.Ahn J.Kim J.-S.Ko K.Park S.Kang Y.-S.Choo Y.-K.
Ewha Authors
박성수
Issue Date
2013
Journal Title
Entomological Research
ISSN
1738-2297JCR Link
Citation
vol. 43, no. 2, pp. 101 - 107
Indexed
SCIE; SCOPUS WOS scopus
Abstract
A male silkworm pupae extract with herbal mixtures such as Rubus coreanusMiquel, Chinese matrimony vine Acanthopanax senticosus and tocopherol can be effectively used to recover or boost stamina. In this study, the effect of the male silkworm pupae extract on the reproductive system of Sprague-Dawley male rats was investigated. No clinical symptoms, and no dying or dead animals were found among experimental male silkworm larvae extract, male silkworm pupae extract and control rat groups during the study. No significant differences were found in body weights, feed or water consumption, or macroscopic examination among the three groups. No lesion was found upon necropsy. However, sperm in the group treated with male silkworm pupae extract were significantly more active than sperm in the control group. Sperm counts in both male groups treated with male silkworm larvae extract and male silkworm pupae extract were significantly higher than sperm counts in the control group. Analysis of phospholipid-hydroperoxide glutathione peroxidase (PHGPx) gene expression showed that the male silkworm pupae extract increased expression in testes by 26.7%. This study shows that the male silkworm pupae extract has potential to be used to enhance the function of the human reproductive system. © 2013 The Entomological Society of Korea and Wiley Publishing Asia Pty Ltd.
DOI
10.1111/1748-5967.12011
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자연과학대학 > 화학·나노과학전공 > Journal papers
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