Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 신동해 | - |
dc.date.accessioned | 2016-08-28T10:08:05Z | - |
dc.date.available | 2016-08-28T10:08:05Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1744-3091 | - |
dc.identifier.other | OAK-9504 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/223220 | - |
dc.description.abstract | ATktA is the most critical enzyme in the nonoxidative pentose phosphate pathway. It catalyzes the conversion of xylulose 5-phosphate and ribose 5 - phosphate into sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate, and its products are used in the biosynthesis of acetyl-CoA, aromatic amino acids, nucleic acids and ADP-l-glycero-β-d-manno-heptose. TktA also has an unexpected role in chromosome structure that is independent of its metabolic responsibilities. Therefore, it is a new potent antibiotic target. In this study, TktA from Burkholderia pseudomallei has been cloned, expressed, purified and crystallized. Synchrotron X-ray data were also collected to 2.0 A resolution. The crystal belonged to the monoclinic space group C2, with unit-cell parameters a = 146.2, b = 74.6, c = 61.6 A, β = 113.0°. A full structural determination is under way in order to provide insight into the structure-function relationship of this protein. © 2012. © 2012 International Union of Crystallography All rights reserved. | - |
dc.language | English | - |
dc.title | A preliminary X-ray study of transketolase from Burkholderia pseudomallei | - |
dc.type | Article | - |
dc.relation.issue | 12 | - |
dc.relation.volume | 68 | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 1554 | - |
dc.relation.lastpage | 1556 | - |
dc.relation.journaltitle | Acta Crystallographica Section F: Structural Biology and Crystallization Communications | - |
dc.identifier.doi | 10.1107/S1744309112044375 | - |
dc.identifier.wosid | WOS:000311693300029 | - |
dc.identifier.scopusid | 2-s2.0-84870925001 | - |
dc.author.google | Kim M.-S. | - |
dc.author.google | Lim A. | - |
dc.author.google | Yang S.W. | - |
dc.author.google | Lee D. | - |
dc.author.google | Park J. | - |
dc.author.google | Shin D.H. | - |
dc.contributor.scopusid | 신동해(57217374185) | - |
dc.date.modifydate | 20230208115524 | - |