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dc.contributor.author정낙신-
dc.date.accessioned2016-08-28T10:08:49Z-
dc.date.available2016-08-28T10:08:49Z-
dc.date.issued2012-
dc.identifier.issn0253-2964-
dc.identifier.otherOAK-9257-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/223044-
dc.description.abstractK-7174, a GATA-specific inhibitor, is a putative anti-inflammatory agent that attenuates effects of inflammatory cytokines in certain cell types. An expeditious four-step synthesis of K-7174 is described in this paper. The route employs Wittig olefination and bis-alkylation of homopiperazine as the key reactions. The iodinecatalyzed isomerization of the Z-isomer results in complete conversion to the E-isomer is the highlight of our synthetic endeavors.-
dc.languageEnglish-
dc.titleA straightforward synthesis of K-7174, a GATA-specific inhibitor-
dc.typeArticle-
dc.relation.issue9-
dc.relation.volume33-
dc.relation.indexSCI-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage2903-
dc.relation.lastpage2906-
dc.relation.journaltitleBulletin of the Korean Chemical Society-
dc.identifier.doi10.5012/bkcs.2012.33.9.2903-
dc.identifier.wosidWOS:000309307400015-
dc.identifier.scopusid2-s2.0-84866405816-
dc.author.googleMajik M.S.-
dc.author.googleYu J.H.-
dc.author.googleJeong L.S.-
dc.date.modifydate20180104081001-
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약학대학 > 약학과 > Journal papers
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