Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 남원우 | * |
dc.contributor.author | 조재흥 | * |
dc.date.accessioned | 2016-08-28T10:08:28Z | - |
dc.date.available | 2016-08-28T10:08:28Z | - |
dc.date.issued | 2012 | * |
dc.identifier.issn | 0002-7863 | * |
dc.identifier.other | OAK-8999 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/222830 | - |
dc.description.abstract | Metal-superoxo species are believed to play key roles in oxygenation reactions by metalloenzymes. One example is cysteine dioxygenase (CDO) that catalyzes the oxidation of cysteine with O 2, and an iron(III)-superoxo species is proposed as an intermediate that effects the sulfoxidation reaction. We now report the first biomimetic example showing that a chromium(III)-superoxo complex bearing a macrocyclic TMC ligand, [Cr III(O 2)(TMC)(Cl)] +, is an active oxidant in oxygen atom transfer (OAT) reactions, such as the oxidation of phosphine and sulfides. The electrophilic character of the Cr(III)-superoxo complex is demonstrated unambiguously in the sulfoxidation of para-substituted thioanisoles. A Cr(IV)-oxo complex, [Cr IV(O)(TMC)(Cl)] +, formed in the OAT reactions by the chromium(III)-superoxo complex, is characterized by X-ray crystallography and various spectroscopic methods. The present results support the proposed oxidant and mechanism in CDO, such as an iron(III)-superoxo species is an active oxidant that attacks the sulfur atom of the cysteine ligand by the terminal oxygen atom of the superoxo group, followed by the formation of a sulfoxide and an iron(IV)-oxo species via an O-O bond cleavage. © 2012 American Chemical Society. | * |
dc.language | English | * |
dc.title | A chromium(III)-superoxo complex in oxygen atom transfer reactions as a chemical model of cysteine dioxygenase | * |
dc.type | Article | * |
dc.relation.issue | 27 | * |
dc.relation.volume | 134 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 11112 | * |
dc.relation.lastpage | 11115 | * |
dc.relation.journaltitle | Journal of the American Chemical Society | * |
dc.identifier.doi | 10.1021/ja304357z | * |
dc.identifier.wosid | WOS:000306297600016 | * |
dc.identifier.scopusid | 2-s2.0-84863811566 | * |
dc.author.google | Cho J. | * |
dc.author.google | Woo J. | * |
dc.author.google | Nam W. | * |
dc.contributor.scopusid | 남원우(7006569723) | * |
dc.contributor.scopusid | 조재흥(7403536408) | * |
dc.date.modifydate | 20240116111857 | * |