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Walking motion of an overdamped active particle in a ratchet potential

Title
Walking motion of an overdamped active particle in a ratchet potential
Authors
Lee K.-J.-B.Kim C.K.Chung M.-H.
Ewha Authors
이공주복
SCOPUS Author ID
이공주복scopus
Issue Date
2012
Journal Title
Journal of Biological Physics
ISSN
0092-0606JCR Link
Citation
vol. 38, no. 2, pp. 305 - 316
Indexed
SCIE; SCOPUS WOS scopus
Abstract
An active particle can convert its internal energy into mechanical work. We study a generalized energy-depot model of an overdamped active particle in a ratchet potential. Using well-known biological parameters for kinesin-1 and modeling ATP influx as a pulsed energy supply, we apply our model to the molecular motor system. We find that our simple model can capture the essential properties of the kinesin motor such as forward stepping, stalling, backward stepping, dependence on ATP concentration, and stall force. Our model might be quite universal in the sense that it is able to describe dynamics of various types of motors as long as realistic parameters for each motor species are adopted. © Springer Science+Business Media B.V. 2011.
DOI
10.1007/s10867-011-9249-1
Appears in Collections:
자연과학대학 > 물리학전공 > Journal papers
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