Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유충규 | - |
dc.date.accessioned | 2016-08-28T12:08:43Z | - |
dc.date.available | 2016-08-28T12:08:43Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0960-894X | - |
dc.identifier.other | OAK-8309 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/222227 | - |
dc.description.abstract | 6,7-Bis(arylthio)-quinazoline-5,8-dione and furo[2,3-f]quinazolin-5-ol derivatives were synthesized and tested for in vitro antifungal activity against Candida, Aspergillus species, and Cryptococcus neoformans. Among them tested, many of furo[2,3-f]quinazolin-5-ols and 6,7-bis(arylthio)-quinazoline-5,8-diones showed good antifungal activity. The compounds 4a and 4e completely inhibited the growth of all against Candida and Aspergillus species tested at the MIC level of 12.5 μg/mL. The results suggest that furo[2,3-f]quinazolin-5-ols and 6,7-bis(arylthio)-quinazoline-5,8-diones would be promising antifungal agents. © 2011 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.title | Synthesis and antifungal activity of 6,7-bis(arylthio)-quinazoline-5,8- diones and furo[2,3-f]quinazolin-5-ols | - |
dc.type | Article | - |
dc.relation.issue | 1 | - |
dc.relation.volume | 22 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 500 | - |
dc.relation.lastpage | 503 | - |
dc.relation.journaltitle | Bioorganic and Medicinal Chemistry Letters | - |
dc.identifier.doi | 10.1016/j.bmcl.2011.10.099 | - |
dc.identifier.wosid | WOS:000298636700098 | - |
dc.identifier.scopusid | 2-s2.0-84655163458 | - |
dc.author.google | Ryu C.-K. | - |
dc.author.google | Kim Y.H. | - |
dc.author.google | Im H.A. | - |
dc.author.google | Kim J.Y. | - |
dc.author.google | Yoon J.H. | - |
dc.author.google | Kim A. | - |
dc.contributor.scopusid | 유충규(15846918400) | - |
dc.date.modifydate | 20170901081001 | - |