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Synthesis and antifungal evaluation of pyrido[1,2-a]indole-1,4-diones and benzo[f]pyrido[1,2-a]indole-6,11-diones

Title
Synthesis and antifungal evaluation of pyrido[1,2-a]indole-1,4-diones and benzo[f]pyrido[1,2-a]indole-6,11-diones
Authors
Ryu C.-K.Yoon J.H.Song A.L.Im H.A.Kim J.Y.Kim A.
Ewha Authors
유충규
SCOPUS Author ID
유충규scopus
Issue Date
2012
Journal Title
Bioorganic and Medicinal Chemistry Letters
ISSN
0960-894XJCR Link
Citation
vol. 22, no. 1, pp. 497 - 499
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Pyrido[1,2-a]indole-1,4-diones and benzo[f]pyrido[1,2-a]indole-6,11-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among them tested, many compounds showed good antifungal activity. The results suggest that pyrido[1,2-a]indole-1,4-diones and benzo[f]pyrido[1,2-a]indole-6,11-diones would be potent antifungal agents. © 2011 Elsevier Ltd. All rights reserved.
DOI
10.1016/j.bmcl.2011.10.092
Appears in Collections:
약학대학 > 약학과 > Journal papers
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