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Regio- and stereoselective synthesis of truncated 3′- aminocarbanucleosides and their binding affinity at the A 3 adenosine receptor

Title
Regio- and stereoselective synthesis of truncated 3′- aminocarbanucleosides and their binding affinity at the A 3 adenosine receptor
Authors
Choi M.J.Chandra G.Lee H.W.Hou X.Choi W.J.Phan K.Jacobson K.A.Jeong L.S.
Ewha Authors
정낙신최원준
Issue Date
2011
Journal Title
Organic and Biomolecular Chemistry
ISSN
1477-0520JCR Link
Citation
vol. 9, no. 20, pp. 6955 - 6962
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
The stereoselective synthesis of truncated 3′-aminocarbanucleosides 4a-dvia a stereo- and regioselective conversion of a diol 9 to bromoacetate 11a and their binding affinity towards the human A 3 adenosine receptor are described. © 2011 The Royal Society of Chemistry.
DOI
10.1039/c1ob05853c
Appears in Collections:
약학대학 > 약학과 > Journal papers
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