NL repository
menu
검색
Library
Browse
Communities & Collections
By Date
Authors
Titles
Subject
My Repository
My Account
Receive email updates
Edit Profile
DSpace at EWHA
의과대학
의학과
Journal papers
View : 536 Download: 0
Pro-inflammatory cytokine expression of spleen dendritic cells in mouse toxoplasmosis
Title
Pro-inflammatory cytokine expression of spleen dendritic cells in mouse toxoplasmosis
Authors
Nam H.-W.
;
Ahn H.-J.
;
Yang H.-J.
Ewha Authors
양현종
SCOPUS Author ID
양현종
Issue Date
2011
Journal Title
Korean Journal of Parasitology
ISSN
0023-4001
Citation
Korean Journal of Parasitology vol. 49, no. 2, pp. 109 - 114
Indexed
SCIE; SCOPUS; KCI
Document Type
Article
Abstract
Dendritic cells have been known as a member of strong innate immune cells against infectious organelles. In this study, we evaluated the cytokine expression of splenic dendritic cells in chronic mouse toxoplasmosis by tissue cyst-forming Me49 strain and demonstrated the distribution of lymphoid dendritic cells by fluorescence-activated cell sorter (FACS). Pro-inflammatory cytokines, such as IL-1α, IL-1β, IL-6, and IL-10 increased rapidly at week 1 post-infection (PI) and peaked at week 3 PI. Serum IL-10 level followed the similar patterns. FACS analysis showed that the number of CD8α +/ CD11c + splenic dendritic cells increased at week 1 and peaked at week 3 PI. In conclusion, mouse splenic dendritic cells showed early and rapid cytokine changes and may have important protective roles in early phases of murine toxoplasmosis. © 2011, Korean Society for Parasitology.
DOI
10.3347/kjp.2011.49.2.109
Appears in Collections:
의과대학
>
의학과
>
Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML
Show full item record
Find@EWHA
트윗하기
BROWSE
Communities & Collections
By Date
Authors
Titles
Subject