Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 양현종 | - |
dc.date.accessioned | 2016-08-28T12:08:59Z | - |
dc.date.available | 2016-08-28T12:08:59Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0023-4001 | - |
dc.identifier.other | OAK-7790 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/221797 | - |
dc.description.abstract | Dendritic cells have been known as a member of strong innate immune cells against infectious organelles. In this study, we evaluated the cytokine expression of splenic dendritic cells in chronic mouse toxoplasmosis by tissue cyst-forming Me49 strain and demonstrated the distribution of lymphoid dendritic cells by fluorescence-activated cell sorter (FACS). Pro-inflammatory cytokines, such as IL-1α, IL-1β, IL-6, and IL-10 increased rapidly at week 1 post-infection (PI) and peaked at week 3 PI. Serum IL-10 level followed the similar patterns. FACS analysis showed that the number of CD8α +/ CD11c + splenic dendritic cells increased at week 1 and peaked at week 3 PI. In conclusion, mouse splenic dendritic cells showed early and rapid cytokine changes and may have important protective roles in early phases of murine toxoplasmosis. © 2011, Korean Society for Parasitology. | - |
dc.language | English | - |
dc.title | Pro-inflammatory cytokine expression of spleen dendritic cells in mouse toxoplasmosis | - |
dc.type | Article | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 49 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 109 | - |
dc.relation.lastpage | 114 | - |
dc.relation.journaltitle | Korean Journal of Parasitology | - |
dc.identifier.doi | 10.3347/kjp.2011.49.2.109 | - |
dc.identifier.wosid | WOS:000292868200002 | - |
dc.identifier.scopusid | 2-s2.0-79959859114 | - |
dc.author.google | Nam H.-W. | - |
dc.author.google | Ahn H.-J. | - |
dc.author.google | Yang H.-J. | - |
dc.contributor.scopusid | 양현종(7406561974) | - |
dc.date.modifydate | 20180329112215 | - |