Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권영주 | * |
dc.date.accessioned | 2016-08-28T12:08:58Z | - |
dc.date.available | 2016-08-28T12:08:58Z | - |
dc.date.issued | 2011 | * |
dc.identifier.issn | 0223-5234 | * |
dc.identifier.other | OAK-7782 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/221789 | - |
dc.description.abstract | Designed and synthesized were a series of 5H-chromeno[4,3-b]pyridines with substitution at 2- and 4-positions with various 5- or 6-membered heteroaromatics as antitumor agents. They were evaluated for topoisomerase I and II inhibitory activities as well as cytotoxicities against several human cancer cell lines. Structure-activity relationship study showed that 2-furyl or 2-thienyl at 2- or 4-position of central pyridine is crucial in displaying topo I or II inhibitory activity and cytotoxicity. © 2011 Elsevier Masson SAS. All rights reserved. | * |
dc.language | English | * |
dc.title | Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase i and II inhibitory activity, cytotoxicity, and structure-activity relationship | * |
dc.type | Article | * |
dc.relation.issue | 8 | * |
dc.relation.volume | 46 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 3201 | * |
dc.relation.lastpage | 3209 | * |
dc.relation.journaltitle | European Journal of Medicinal Chemistry | * |
dc.identifier.doi | 10.1016/j.ejmech.2011.04.029 | * |
dc.identifier.wosid | WOS:000292670000003 | * |
dc.identifier.scopusid | 2-s2.0-79958283748 | * |
dc.author.google | Thapa U. | * |
dc.author.google | Thapa P. | * |
dc.author.google | Karki R. | * |
dc.author.google | Yun M. | * |
dc.author.google | Choi J.H. | * |
dc.author.google | Jahng Y. | * |
dc.author.google | Lee E. | * |
dc.author.google | Jeon K.-H. | * |
dc.author.google | Na Y. | * |
dc.author.google | Ha E.-M. | * |
dc.author.google | Cho W.-J. | * |
dc.author.google | Kwon Y. | * |
dc.author.google | Lee E.-S. | * |
dc.contributor.scopusid | 권영주(12446435600) | * |
dc.date.modifydate | 20240422124907 | * |