Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤여준 | * |
dc.contributor.author | 박제원 | * |
dc.date.accessioned | 2016-08-28T12:08:53Z | - |
dc.date.available | 2016-08-28T12:08:53Z | - |
dc.date.issued | 2011 | * |
dc.identifier.issn | 1017-7825 | * |
dc.identifier.other | OAK-7734 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/221747 | - |
dc.description.abstract | Streptomyces venezuelae YJ028, bearing a deletion of the entire biosynthetic gene cluster encoding the pikromycin polyketide synthases and desosamine biosynthetic enzymes, was used as a bioconversion system for combinatorial biosynthesis of glycosylated derivatives of tylosin. Two engineered deoxysugar biosynthetic pathways for the biosynthesis of TDP-3-O-demethyl-D-chalcose or TDP-Lrhamnose in conjunction with the glycosyltransferaseauxiliary protein pair DesVII/DesVIII were expressed in a S. venezuelae YJ028 mutant strain. Supplementation of each mutant strain capable of producing TDP-3-O-demethyl- D-chalcose or TDP-L-rhamnose with tylosin aglycone tylactone resulted in the production of the 3-O-demethyl- D-chalcose, D-quinovose, or L-rhamnose-glycosylated tylactone. © The Korean Society for Microbiology and Biotechnology. | * |
dc.language | English | * |
dc.title | Biosynthesis of glycosylated derivatives of tylosin in Streptomyces venezuelae | * |
dc.type | Article | * |
dc.relation.issue | 6 | * |
dc.relation.volume | 21 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 613 | * |
dc.relation.lastpage | 616 | * |
dc.relation.journaltitle | Journal of Microbiology and Biotechnology | * |
dc.identifier.doi | 10.4014/jmb.1103.03032 | * |
dc.identifier.wosid | WOS:000292178200009 | * |
dc.identifier.scopusid | 2-s2.0-79960021430 | * |
dc.author.google | Han A.R. | * |
dc.author.google | Park S.R. | * |
dc.author.google | Park J.W. | * |
dc.author.google | Lee E.Y. | * |
dc.author.google | Kim D.-M. | * |
dc.author.google | Kim B.-G. | * |
dc.author.google | Yoon Y.J. | * |
dc.contributor.scopusid | 윤여준(7402126465) | * |
dc.date.modifydate | 20240405124244 | * |