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Anti-respiratory syncytial virus (RSV) activity of timosaponin A-III from the rhizomes of Anemarrhena asphodeloides

Title
Anti-respiratory syncytial virus (RSV) activity of timosaponin A-III from the rhizomes of Anemarrhena asphodeloides
Authors
Youn U.J.Jang J.-E.Nam J.-W.Lee Y.J.Son Y.M.Shin H.J.Han A.-R.Chang J.Seo E.-K.
Ewha Authors
서은경장준한아름윤의중
SCOPUS Author ID
서은경scopus; 장준scopus; 한아름scopusscopus
Issue Date
2011
Journal Title
Journal of Medicinal Plants Research
ISSN
1996-0875JCR Link
Citation
vol. 5, no. 7, pp. 1062 - 1065
Indexed
SCOPUS WOS scopus
Abstract
Two known steroidal saponins, timosaponin A-III (1) and anemarsaponin B (2) were isolated from the BuOH fraction of the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae) together with the xanthone derivatives, mangiferin (3) and neomangiferin (4). Structures of the isolates were identified using 1D and 2D NMR techniques and by comparison with the published values. Timosaponin A-III (1) exhibited potent inhibitory effects on the respiratory syncytial virus (RSV), with an IC 50 value of 1.00 μM. ©2011 Academic Journals.
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약학대학 > 약학과 > Journal papers
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