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Fluorescent sensing of triphosphate nucleotides via anthracene derivatives
- Title
- Fluorescent sensing of triphosphate nucleotides via anthracene derivatives
- Authors
- Kim H.N.; Moon J.H.; Kim S.K.; Kwon J.Y.; Jang Y.J.; Lee J.Y.; Yoon J.
- Ewha Authors
- 윤주영
- SCOPUS Author ID
- 윤주영
- Issue Date
- 2011
- Journal Title
- Journal of Organic Chemistry
- ISSN
- 0022-3263
- Citation
- Journal of Organic Chemistry vol. 76, no. 10, pp. 3805 - 3811
- Indexed
- SCI; SCIE; SCOPUS
- Document Type
- Article
- Abstract
- A nucleotide is composed of a nucleobase, a five-carbon sugar, and phosphate groups. Recognition of these three sites can provide useful information for the development of selective fluorescent receptors for a specific nucleotide. In this paper, anthracene derivatives with two imidazolium groups at the 1,8- and 9,10-positions, quaternary ammonium groups, or the boronic acid group were examined for the recognition of nucleotides, such as ATP, GTP, CTP, TTP, UTP, ADP, and AMP, via fluorescence changes. The anthracene group provides the interaction between the bases of the nucleotides. The imidazolium and quaternary ammonium groups induce hydrogen bonding interactions with the phosphate groups of the nucleotides. The boronic acid group can interact with the ribose of the nucleotides. © 2011 American Chemical Society.
- DOI
- 10.1021/jo2000836
- Appears in Collections:
- 자연과학대학 > 화학·나노과학전공 > Journal papers
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