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Simple fabrication of hydrophilic nanochannels using the chemical bonding between activated ultrathin PDMS layer and cover glass by oxygen plasma

Title
Simple fabrication of hydrophilic nanochannels using the chemical bonding between activated ultrathin PDMS layer and cover glass by oxygen plasma
Authors
Kim S.H.Cui Y.Lee M.J.Nam S.-W.Oh D.Kang S.H.Kim Y.S.Park S.
Ewha Authors
박성수남성원
Issue Date
2011
Journal Title
Lab on a Chip - Miniaturisation for Chemistry and Biology
ISSN
1473-0197JCR Link
Citation
vol. 11, no. 2, pp. 348 - 353
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
This study describes a simple and low cost method for fabricating enclosed transparent hydrophilic nanochannels by coating low-viscosity PDMS (monoglycidyl ether-terminated polydimethylsiloxane) as an adhesion layer onto the surface of the nanotrenches that are molded with a urethane-based UV-curable polymer, Norland Optical Adhesive (NOA 63). In detail, the nanotrenches made of NOA 63 were replicated from a Si master mold and coated with 6 nm thick layer of PDMS. These nanotrenches underwent an oxygen plasma treatment and finally were bound to a cover glass by chemical bonding between silanol and hydroxyl groups. Hydrophobic recovery that is observed in the bulk PDMS was not observed in the thin film of PDMS on the mold and the PDMS-coated nanochannel maintained its surface hydrophilicity for at least one month. The potentials of the nanochannels for bioapplications were demonstrated by stretching λ-DNA (48,502 bp) in the channels. Therefore, this fabrication approach provides a practical solution for the simple fabrication of the nanochannels for bioapplications. © 2011 The Royal Society of Chemistry.
DOI
10.1039/c0lc00015a
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자연과학대학 > 화학·나노과학전공 > Journal papers
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