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dc.contributor.author이화정-
dc.date.accessioned2016-08-28T12:08:40Z-
dc.date.available2016-08-28T12:08:40Z-
dc.date.issued2010-
dc.identifier.issn1079-9907-
dc.identifier.otherOAK-6885-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/221034-
dc.description.abstractThe transforming growth factor-β1 (TGF-β1) bioassay developed in this study monitors increased luciferase activity in MCF10A cells containing the matrix metalloproteinase-2 (MMP-2) promoter with a luciferase reporter and treated with increasing TGF-β1 concentrations. The response was linear in the concentration range from 75 to 2,500pg/mL. The abilities of 3 types of TGF-β in inducing MMP-2 were different. The luciferase activity induced by TGF-β1 was about 2 times more than that by TGF-β2 and TGF-β3. The MMP-2 promoter bioassay showed greater reproducibility (coefficient of variation [CV] 10%) than the previously developed anticell proliferation assay of TF-1 cell (CV 16%) and the MMP-2 zymogram assay (CV 40%). Mary Ann Liebert, Inc.-
dc.languageEnglish-
dc.titleTransforming growth factor-β1 bioassay involving matrix metalloproteinase-2 induction-
dc.typeArticle-
dc.relation.issue9-
dc.relation.volume30-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage667-
dc.relation.lastpage672-
dc.relation.journaltitleJournal of Interferon and Cytokine Research-
dc.identifier.doi10.1089/jir.2009.0058-
dc.identifier.wosidWOS:000281861800005-
dc.identifier.scopusid2-s2.0-77956561630-
dc.author.googleKim G.-H.-
dc.author.googleKang S.-Y.-
dc.author.googleKwak H.-J.-
dc.author.googleBaek K.-M.-
dc.author.googleHong S.-H.-
dc.author.googleLee H.-J.-
dc.author.googleSohn Y.-W.-
dc.contributor.scopusid이화정(35069834100)-
dc.date.modifydate20170601134554-
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약학대학 > 약학과 > Journal papers
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