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Photoinduced DNA cleavage by formation of ROS from oxygen with a neurotransmitter and aromatic amino acids

Title
Photoinduced DNA cleavage by formation of ROS from oxygen with a neurotransmitter and aromatic amino acids
Authors
Kawashima T.Ohkubo K.Fukuzumi S.
Ewha Authors
Shunichi Fukuzumi
SCOPUS Author ID
Shunichi Fukuzumiscopus
Issue Date
2010
Journal Title
Organic and Biomolecular Chemistry
ISSN
1477-0520JCR Link
Citation
vol. 8, no. 5, pp. 994 - 996
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
UV-B photoirradiation of a neurotransmitter (serotonin) and aromatic amino acids (tryptophan and tyrosine) with oxygen results in DNA cleavage by generation of reactive oxygen species (ROS) as demonstrated by agarose gel electrophoresis with pBR 322 DNA, ESR and laser flash photolysis measurements. © The Royal Society of Chemistry.
DOI
10.1039/b924560j
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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