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dc.contributor.author이병구-
dc.date.accessioned2016-08-28T12:08:45Z-
dc.date.available2016-08-28T12:08:45Z-
dc.date.issued2010-
dc.identifier.issn0066-4804-
dc.identifier.otherOAK-6233-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/220496-
dc.description.abstractAfter intravenous or oral administration of 10 mg/kg itraconazole to rats with streptozotocin-induced diabetes mellitus and to control rats, the total area under the plasma concentration-time curve from time 0 to 24 h (AUC 0-24) for itraconazole and that for its metabolite, 7-hydroxyitraconazole, were similar between the two groups of rats. This may be explained by the comparable hepatic and intestinal intrinsic clearance rates for the disappearance of itraconazole and the formation of 7-hydroxyitraconazole in both groups of rats. Copyright © 2010, American Society for Microbiology. All Rights Reserved.-
dc.languageEnglish-
dc.titlePharmacokinetics of itraconazole in diabetic rats-
dc.typeArticle-
dc.relation.issue2-
dc.relation.volume54-
dc.relation.indexSCI-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage931-
dc.relation.lastpage933-
dc.relation.journaltitleAntimicrobial Agents and Chemotherapy-
dc.identifier.doi10.1128/AAC.01145-09-
dc.identifier.wosidWOS:000273860600050-
dc.identifier.scopusid2-s2.0-75749111334-
dc.author.googleLee U.-
dc.author.googleChoi Y.H.-
dc.author.googleKim S.H.-
dc.author.googleLee B.K.-
dc.contributor.scopusid이병구(55502906900;55758384300)-
dc.date.modifydate20200303081002-


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