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Electrospinning of polysaccharides for regenerative medicine

Title
Electrospinning of polysaccharides for regenerative medicine
Authors
Lee K.Y.Jeong L.Kang Y.O.Lee S.J.Park W.H.
Ewha Authors
이승진
SCOPUS Author ID
이승진scopus
Issue Date
2009
Journal Title
Advanced Drug Delivery Reviews
ISSN
0169-409XJCR Link
Citation
vol. 61, no. 12, pp. 1020 - 1032
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Electrospinning techniques enable the production of continuous fibers with dimensions on the scale of nanometers from a wide range of natural and synthetic polymers. The number of recent studies regarding electrospun polysaccharides and their derivatives, which are potentially useful for regenerative medicine, is increasing dramatically. However, difficulties regarding the processibility of the polysaccharides (e.g., poor solubility and high surface tension) have limited their application. In this review, we summarize the characteristics of various polysaccharides such as alginate, cellulose, chitin, chitosan, hyaluronic acid, starch, dextran, and heparin, which are either currently being used or have potential to be used for electrospinning. The recent progress of nanofiber matrices electrospun from polysaccharides and their biomedical applications in tissue engineering, wound dressings, drug delivery, and enzyme immobilization are discussed. © 2009 Elsevier B.V. All rights reserved.
DOI
10.1016/j.addr.2009.07.006
Appears in Collections:
약학대학 > 약학과 > Journal papers
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