Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤주영 | * |
dc.contributor.author | 박성수 | * |
dc.date.accessioned | 2016-08-28T12:08:28Z | - |
dc.date.available | 2016-08-28T12:08:28Z | - |
dc.date.issued | 2009 | * |
dc.identifier.issn | 0002-7863 | * |
dc.identifier.other | OAK-6011 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/220313 | - |
dc.description.abstract | A pincer-like benzene-bridged sensor 1 with a pyrene excimer as a signal source and imidazolium as a phosphate anion receptor was synthesized and investigated for ATP sensing. A unique switch of excimer vs monomer pyrene fluorescence of 1 is observed in the presence of ATP due to the charcteristic sandwich π-π stacking of pyrene-adenine-pyrene. On the other hand, four other bases of nucleoside triphosphates such as GTP, CTP, UTP, and TTP can interact only from the outside with the already stabilized stacked pyrene-pyrene dimer of 1, resulting in excimer fluorescence quenching. The fluorescent intensity ratio of monomer-to-excimer for 1 upon binding with ATP (I 375/I 487) is much larger than that upon binding with ADP and AMP. This difference is large enough to discriminate ATP from ADP and AMP. As one of the biological applications, sensor 1 is successfully applied to the ATP staining experiments. Sensor 1 is also applied to monitor the hydrolysis of ATP and ADP by apyrase. The results indicate that 1 is a useful fluorescent sensor for investigations of ATP-relevant biological processes. © 2009 American Chemical Society. | * |
dc.language | English | * |
dc.title | Unique sandwich stacking of pyrene-adenine-pyrene for selective and ratiometric fluorescent sensing of ATP at physiological pH | * |
dc.type | Article | * |
dc.relation.issue | 42 | * |
dc.relation.volume | 131 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 15528 | * |
dc.relation.lastpage | 15533 | * |
dc.relation.journaltitle | Journal of the American Chemical Society | * |
dc.identifier.doi | 10.1021/ja906855a | * |
dc.identifier.wosid | WOS:000271272000074 | * |
dc.identifier.scopusid | 2-s2.0-70350328017 | * |
dc.author.google | Xu Z. | * |
dc.author.google | Singh N.J. | * |
dc.author.google | Lim J. | * |
dc.author.google | Pan J. | * |
dc.author.google | Ha N.K. | * |
dc.author.google | Park S. | * |
dc.author.google | Kim K.S. | * |
dc.author.google | Yoon J. | * |
dc.contributor.scopusid | 윤주영(7403587371) | * |
dc.contributor.scopusid | 박성수(9275920900;41262153700) | * |
dc.date.modifydate | 20240118162450 | * |