DSpace at EWHA: Synthesis of isoquinolinone-based tetracycles as poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors

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DC Field	Value	Language
dc.contributor.author	박혜영	*
dc.contributor.author	권영주	*
dc.date.accessioned	2016-08-28T12:08:26Z	-
dc.date.available	2016-08-28T12:08:26Z	-
dc.date.issued	2009	*
dc.identifier.issn	0968-0896	*
dc.identifier.other	OAK-5989	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/220298	-
dc.description.abstract	The isoquinolinone-based tetracyclic compounds were designed and synthesized and their PARP-I inhibitory activity was evaluated. Most of synthesized compounds showed fairly good activity. Also the most active compound 6 showed its activity on potentiation of anticancer agents, temozolamide and etoposide, by 1.7 times, respectively. © 2009 Elsevier Ltd. All rights reserved.	*
dc.language	English	*
dc.title	Synthesis of isoquinolinone-based tetracycles as poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors	*
dc.type	Article	*
dc.relation.issue	21	*
dc.relation.volume	17	*
dc.relation.index	SCI	*
dc.relation.index	SCIE	*
dc.relation.index	SCOPUS	*
dc.relation.startpage	7537	*
dc.relation.lastpage	7541	*
dc.relation.journaltitle	Bioorganic and Medicinal Chemistry	*
dc.identifier.doi	10.1016/j.bmc.2009.09.014	*
dc.identifier.wosid	WOS:000270903100017	*
dc.identifier.scopusid	2-s2.0-73949157710	*
dc.author.google	Rhee H.-K.	*
dc.author.google	Lim S.Y.	*
dc.author.google	Jung M.-J.	*
dc.author.google	Kwon Y.	*
dc.author.google	Kim M.-H.	*
dc.author.google	Choo H.-Y.P.	*
dc.contributor.scopusid	박혜영(34972649500;57200273796)	*
dc.contributor.scopusid	권영주(12446435600)	*
dc.date.modifydate	20240422124907	*