Bulletin of the Korean Chemical Society vol. 29, no. 12, pp. 2487 - 2490
Indexed
SCI; SCIE; SCOPUS; KCI
Document Type
Article
Abstract
5''-Iodoneplanocin A (1) and its analogues 2 and 3 were designed and synthesized as potential SAHH inhibitor via iodocyclopentenol 6, which was prepared using a Michael addition-iodination-elimination process. All final compounds did not show antiviral activity, maybe due to a steric hindrance induced by 5″-iodo substituent.