View : 16 Download: 0

Synthesis of methyl-substituted bicyclic carbanucleoside analogs as potential antiherpetic agents

Title
Synthesis of methyl-substituted bicyclic carbanucleoside analogs as potential antiherpetic agents
Authors
Kim K.R.Park A.-Y.Lee H.-R.Kang J.-A.Won H.K.Chun P.Jang H.B.Lak S.J.Hyung R.M.
Ewha Authors
정낙신
Issue Date
2008
Journal Title
Bulletin of the Korean Chemical Society
ISSN
0253-2964JCR Link
Citation
vol. 29, no. 10, pp. 1977 - 1982
Indexed
SCI; SCIE; SCOPUS; KCI WOS scopus
Abstract
Novel bicyclo[3.1.0]hexanyl purine nucleoside analogues were synthesized as potential antiherpetic agents via a bicyclo[3.1.0]hexanol (±)-8, which was prepared using a highly efficient carbenoid cycloaddition reaction. A highly diastereoselective reduction of ketone and a Mitsunobu reaction for the condensation of glycosyl donor (±)-12 with 6-chloropurine were employed.
Appears in Collections:
약학대학 > 약학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE