Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이상국 | * |
dc.contributor.author | 서은경 | * |
dc.contributor.author | 한아름 | * |
dc.date.accessioned | 2016-08-28T12:08:03Z | - |
dc.date.available | 2016-08-28T12:08:03Z | - |
dc.date.issued | 2008 | * |
dc.identifier.issn | 0009-2363 | * |
dc.identifier.other | OAK-5047 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/220060 | - |
dc.description.abstract | A new naphthoquinone, (-)-3-[2-(acetyloxy)propyl]-2-hydroxy-8-methoxy-1,4- naphthoquinone (1) was isolated from the bulb of Eleutherine americana Merr. et Heyne (Iridaceae) together with two known compounds, eleutherinol (6) and 1,5-dihydroxy-3-methylanthraquinone (7) which were found in this species for the first time. The other known compounds, (-)-isoeleutherin (2), (+)-eleutherin (3), (-)-hongconin (4), and (+)-dihydroeleutherinol (5) which were reported previously from this species, were also isolated in the present study. Compounds 2-6 exhibited potent inhibitory activity on nitric oxide production in RAW 264.7 lipopolysaccharide-activated mouse macrophage cells with IC50 values of 7.7, 11.4, 19.8, 21.7, and 34.4 μm, respectively, whereas the other two compounds, 1 and 7, were inactive. The structure of compound 1 was elucidated by spectroscopic data analysis including 1D and 2D NMR experiments. © 2008 Pharmaceutical Society of Japan. | * |
dc.language | English | * |
dc.title | Identification of a new naphthalene and its derivatives from the bulb of Eleutherine americana with inhibitory activity on lipopolysaccharide-induced nitric oxide production | * |
dc.type | Article | * |
dc.relation.issue | 9 | * |
dc.relation.volume | 56 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1314 | * |
dc.relation.lastpage | 1316 | * |
dc.relation.journaltitle | Chemical and Pharmaceutical Bulletin | * |
dc.identifier.doi | 10.1248/cpb.56.1314 | * |
dc.identifier.wosid | WOS:000259078100018 | * |
dc.identifier.scopusid | 2-s2.0-51349083750 | * |
dc.author.google | Han A.-R. | * |
dc.author.google | Min H.-Y. | * |
dc.author.google | Nam J.-W. | * |
dc.author.google | Lee N.-Y. | * |
dc.author.google | Wiryawan A. | * |
dc.author.google | Suprapto W. | * |
dc.author.google | Lee S.K. | * |
dc.author.google | Lee K.R. | * |
dc.author.google | Seo E.-K. | * |
dc.contributor.scopusid | 이상국(36067620500) | * |
dc.contributor.scopusid | 서은경(7005953758) | * |
dc.contributor.scopusid | 한아름(56278315000;34769874800) | * |
dc.date.modifydate | 20240130112016 | * |