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How Do Flies Tolerate Microorganisms in the Gut?

Title
How Do Flies Tolerate Microorganisms in the Gut?
Authors
Lee W.-J.
Ewha Authors
이원재
Issue Date
2008
Journal Title
Cell Host and Microbe
ISSN
1931-3128JCR Link
Citation
vol. 4, no. 2, pp. 91 - 93
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Although gut epithelia are in constant contact with a large number of microbe-derived immune elicitors such as peptidoglycan, they do not mount an intense immune response. In this issue of Cell Host & Microbe, Lhocine et al. (2008) report that the PIMS gene product induces immune tolerance by reducing the availability of the peptidoglycan receptor in the plasma membrane. These findings provide a novel insight into the molecular mechanisms by which the host gut maintains balanced host-microbe interactions. © 2008 Elsevier Inc. All rights reserved.
DOI
10.1016/j.chom.2008.07.007
Appears in Collections:
일반대학원 > 바이오융합과학과 > Journal papers
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