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Which exact test is more powerful in testing the hardy-weinberg law?

Title
Which exact test is more powerful in testing the hardy-weinberg law?
Authors
Kang S.-H.
Ewha Authors
강승호
Issue Date
2008
Journal Title
Communications in Statistics: Simulation and Computation
ISSN
0361-0918JCR Link
Citation
vol. 37, no. 1, pp. 14 - 24
Indexed
SCIE; SCOPUS WOS scopus
Abstract
The asymptotic chi-square test for testing the Hardy-Weinberg law is unreliable in either small or unbalanced samples. As an alternative, either the unconditional or conditional exact test might be used. It is known that the unconditional exact test has greater power than the conditional exact test in small samples. In this article, we show that the conditional exact test is more powerful than the unconditional exact test in large samples. This result is useful in extremely unbalanced cases with large sample sizes which are often obtained when a rare allele exists.
DOI
10.1080/03610910701420065
Appears in Collections:
자연과학대학 > 통계학전공 > Journal papers
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