DSpace at EWHA: Topoisomerase-II-Inhibitory principles from the stems of Spatholobus suberectus

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DC Field	Value	Language
dc.contributor.author	김화정	*
dc.contributor.author	이상국	*
dc.contributor.author	서은경	*
dc.contributor.author	한아름	*
dc.date.accessioned	2016-08-28T12:08:45Z	-
dc.date.available	2016-08-28T12:08:45Z	-
dc.date.issued	2007	*
dc.identifier.issn	1612-1872	*
dc.identifier.other	OAK-4161	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/219883	-
dc.description.abstract	Bioassay-guided fractionation of the stems of Spatholobus suberectus led to the isolation of procyanidin B4 (=(+)-catechin-(4→8)-(-)-epicatechin) (1) and (+)-catechin-(4→8)-(+)-catechin(4→8)-(-)-epicatechin (2). These compounds, isolated before from other sources, were found to be highly potent inhibitors of DNA-topoisomerase-II (Topo-II)-mediated KDNA decatenation, with IC50 values of 22.5 ± 2.3 and 21.9 ±2.2 nM, resp. © 2007 Verlag Helvetica Chimica Acta AG, Zürich.	*
dc.language	English	*
dc.title	Topoisomerase-II-Inhibitory principles from the stems of Spatholobus suberectus	*
dc.type	Article	*
dc.relation.issue	7	*
dc.relation.volume	4	*
dc.relation.index	SCIE	*
dc.relation.index	SCOPUS	*
dc.relation.startpage	1487	*
dc.relation.lastpage	1491	*
dc.relation.journaltitle	Chemistry and Biodiversity	*
dc.identifier.doi	10.1002/cbdv.200790127	*
dc.identifier.wosid	WOS:000248370000007	*
dc.identifier.scopusid	2-s2.0-34547520341	*
dc.author.google	Han A.-R.	*
dc.author.google	Park H.J.	*
dc.author.google	Chen D.	*
dc.author.google	Jang D.S.	*
dc.author.google	Kim H.-J.	*
dc.author.google	Lee S.K.	*
dc.author.google	Seo E.-K.	*
dc.contributor.scopusid	김화정(56670336100)	*
dc.contributor.scopusid	이상국(36067620500)	*
dc.contributor.scopusid	서은경(7005953758)	*
dc.contributor.scopusid	한아름(56278315000;34769874800)	*
dc.date.modifydate	20240130112016	*