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Synthesis and antifungal activity of noble 5-arylamino- and 6-arylthio-4,7-dioxobenzoselenazoles

Title
Synthesis and antifungal activity of noble 5-arylamino- and 6-arylthio-4,7-dioxobenzoselenazoles
Authors
Ryu C.-K.Han J.-Y.Jung O.-J.Lee S.-K.Lee J.Y.Jeong S.H.
Ewha Authors
유충규
SCOPUS Author ID
유충규scopus
Issue Date
2005
Journal Title
Bioorganic and Medicinal Chemistry Letters
ISSN
0960-894XJCR Link
Citation
vol. 15, no. 3, pp. 679 - 682
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
5-Arylamino- and 6-arylthio-4,7-dioxobenzoselenazoles 4 and 5 were synthesized and tested for in vitro antifungal activity against Candida and Aspergillus species. 5-Arylamino-4,7-dioxobenzoselenazoles 4 showed, in general, more potent antifungal activity than 6-arylthio-4,7-dioxobenzoselenazoles 5. The results suggest that 5-arylamino-4,7-dioxobenzoselenazoles 4 would be potent antifungal agents. © 2004 Elsevier Ltd. All rights reserved.
DOI
10.1016/j.bmcl.2004.11.027
Appears in Collections:
약학대학 > 약학과 > Journal papers
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