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Synthesis and cytotoxic activity of 6-(substituted-phenyl)amino-5,8- quinazolinediones

Title
Synthesis and cytotoxic activity of 6-(substituted-phenyl)amino-5,8- quinazolinediones
Authors
Ryu C.-K.Yi Y.-J.Choi I.H.Chae M.J.Han J.-Y.Jung O.-J.Lee C.-O.
Ewha Authors
유충규
SCOPUS Author ID
유충규scopus
Issue Date
2004
Journal Title
Medicinal Chemistry Research
ISSN
1054-2523JCR Link
Citation
vol. 13, no. 5, pp. 249 - 258
Indexed
SCIE; SCOPUS WOS scopus
Abstract
6-Arylamino-5,8-quinazolinediones were synthesized and evaluated for in vitro cytotoxic activity against human solid tumor cell lines A549, SK-OV-3, SK-MEL-2, XF498 and HCT-15. Most of the 6-arylamino-5,8-quinazolinediones exhibited potent activity against the cell lines HCT-15 and SK-MEL-2. © Birkhäuser Boston 2004.
DOI
10.1007/s00044-004-0032-8
Appears in Collections:
약학대학 > 약학과 > Journal papers
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