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약학대학
약학과
Journal papers
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Synthesis and cytotoxic activity of 6-(substituted-phenyl)amino-5,8- quinazolinediones
Title
Synthesis and cytotoxic activity of 6-(substituted-phenyl)amino-5,8- quinazolinediones
Authors
Ryu C.-K.
;
Yi Y.-J.
;
Choi I.H.
;
Chae M.J.
;
Han J.-Y.
;
Jung O.-J.
;
Lee C.-O.
Ewha Authors
유충규
SCOPUS Author ID
유충규
Issue Date
2004
Journal Title
Medicinal Chemistry Research
ISSN
1054-2523
Citation
Medicinal Chemistry Research vol. 13, no. 5, pp. 249 - 258
Indexed
SCIE; SCOPUS
Document Type
Article
Abstract
6-Arylamino-5,8-quinazolinediones were synthesized and evaluated for in vitro cytotoxic activity against human solid tumor cell lines A549, SK-OV-3, SK-MEL-2, XF498 and HCT-15. Most of the 6-arylamino-5,8-quinazolinediones exhibited potent activity against the cell lines HCT-15 and SK-MEL-2. © Birkhäuser Boston 2004.
DOI
10.1007/s00044-004-0032-8
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