Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 오억수 | - |
dc.date.accessioned | 2016-08-28T11:08:39Z | - |
dc.date.available | 2016-08-28T11:08:39Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 1016-8478 | - |
dc.identifier.other | OAK-2147 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/219424 | - |
dc.description.abstract | The vertebrate syndecans, which make up a four-member family of small type I transmembrane heparan sulfate proteoglycans, constitute evolutionarily conserved family proteins. In particular, sequences in the transmembrane and cytoplasmic domains are a unifying feature within the family. However, the extracellular domain sequences are molecule-specific, implying that different syndecans have evolved to carry out similar, but non-identical, functions. While all four syndecans have been implicated in regulation of the cytoskeleton, their roles are clearly complex. Recent developments indicate that the closely related syndecan-2 and -4 have separable functions, though both bind a number of ligands through their heparan sulfate chains. The specification of these activities is probably core protein related, but is it due to a distinct expression pattern or molecule-specific regulatory mechanisms? Although there is not yet enough data to provide unambiguous answers, here we shall review the known functions and regulatory mechanisms of syndecan-2 and -4. ©KSMCB 2004. | - |
dc.language | English | - |
dc.title | Syndecans-2 and -4; close cousins, but not identical twins | - |
dc.type | Review | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 17 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 181 | - |
dc.relation.lastpage | 187 | - |
dc.relation.journaltitle | Molecules and Cells | - |
dc.identifier.wosid | WOS:000221196900001 | - |
dc.identifier.scopusid | 2-s2.0-3442893289 | - |
dc.author.google | Oh E.-S. | - |
dc.author.google | Couchman J.R. | - |
dc.contributor.scopusid | 오억수(7101967153) | - |
dc.date.modifydate | 20190901081003 | - |