View : 43 Download: 0

The inhibitory principle of lipopolysaccharide-induced nitric oxide production from Inula britannica var. chinensis

Title
The inhibitory principle of lipopolysaccharide-induced nitric oxide production from Inula britannica var. chinensis
Authors
Je K.-H.Han A.-R.Lee H.-T.Mar W.Seo E.-K.
Ewha Authors
서은경한아름
SCOPUS Author ID
서은경scopus; 한아름scopusscopus
Issue Date
2004
Journal Title
Archives of Pharmacal Research
ISSN
0253-6269JCR Link
Citation
vol. 27, no. 1, pp. 83 - 85
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
A sesquiterpene lactone, 1-O-acetyl-4 R,6 S-britannilactone (1) isolated from the flowers of Inula britannica L. var. chinensis (Rupr.) Reg. (Compositae), was found as an iNOS inhibitory constituent for the first time with an IC50 value of 22.1 μM which is more potent than the positive control, L-N6-(1-iminoethyl)lysine (IC50 = 33.7 μM). Structure of compound 1 was identified by 1D and 2D NMR experiments and by comparison with the reference standard.
Appears in Collections:
약학대학 > 약학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE