Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유충규 | - |
dc.date.accessioned | 2016-08-28T11:08:10Z | - |
dc.date.available | 2016-08-28T11:08:10Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0253-6269 | - |
dc.identifier.other | OAK-1291 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/219121 | - |
dc.description.abstract | 6,7-Bis-[S-(aryl)thio]-5,8-quinolinediones 4 and 5 were synthesized by the substitution of 6,7-dichloro-5,8-quinolinediones with appropriate arylthiols. Their antifungal activity were tested in vitro for their growth inhibitory activities against pathogenic fungi in comparison with flucytosine. The antifungal activities were significantly improved by S-(aryl)thio moieties of the compounds 4 and 5. The all tested compounds 4 and 5 showed generally good activities against C. albicans and A. niger ranging from 0.8 to 25 μg/ml. Among them, compounds 4d-4h and 5a-5c exhibited also good activities against C. krusei and C. tropicalis. The activities of compounds 4j and 4l were comparable to those of flucytosine against all tested fungi. | - |
dc.language | English | - |
dc.title | Synthesis and antifungal activity of 6,7-Bis-[S-(aryl)thio]-5,8- quinolinediones | - |
dc.type | Article | - |
dc.relation.issue | 6 | - |
dc.relation.volume | 25 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 795 | - |
dc.relation.lastpage | 800 | - |
dc.relation.journaltitle | Archives of Pharmacal Research | - |
dc.identifier.wosid | WOS:000180186000008 | - |
dc.identifier.scopusid | 2-s2.0-0038003901 | - |
dc.author.google | Ryu C.-K. | - |
dc.author.google | Sun Y.-J. | - |
dc.author.google | Shim J.-Y. | - |
dc.author.google | You H.-J. | - |
dc.author.google | Ko U.C. | - |
dc.author.google | Lee H. | - |
dc.contributor.scopusid | 유충규(15846918400) | - |
dc.date.modifydate | 20170901081001 | - |