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Thermosensitive and hydrolysis-sensitive poly(organophosphazenes)

Title
Thermosensitive and hydrolysis-sensitive poly(organophosphazenes)
Authors
Lee B.H.Lee Y.M.Sohn Y.S.Song S.-C.
Ewha Authors
손연수
SCOPUS Author ID
손연수scopus
Issue Date
2002
Journal Title
Polymer International
ISSN
0959-8103JCR Link
Citation
vol. 51, no. 7, pp. 658 - 660
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
The lower critical solution temperature (LCST) properties and hydrolytic behaviour of thermosensitive biodegradable polyphosphazenes with monomethoxy-poly(ethylene glycol), glycine ethyl ester and depsipeptide ethyl esters substituents have been studied. All the polymers synthesized show LCST properties. The LCSTs of the polymers are affected by the composition of the polymers and increase with the degradation of the polymers in aqueous solution. The higher content of depsipeptide ethyl esters in the polymers accelerates the LCST change and the degradation of the polymers in aqueous solution. Most polymers synthesized have half-lives of less than 10 days in neutral solution. © 2002 Society of Chemical Industry.
DOI
10.1002/pi.1019
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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