Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유충규 | * |
dc.contributor.author | 김화정 | * |
dc.date.accessioned | 2016-08-28T11:08:56Z | - |
dc.date.available | 2016-08-28T11:08:56Z | - |
dc.date.issued | 2002 | * |
dc.identifier.issn | 0223-5234 | * |
dc.identifier.other | OAK-981 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/218959 | - |
dc.description.abstract | 6-(Substituted-phenyl)amino-5,8-quinazolinediones (3) were synthesised by regioselective substitution of 5,8-quinazolinedione (5) with appropriate arylamines in the presence of Ce(III) ions. All synthesised 5,8-quinazolinediones 3 showed a potent and efficacious inhibitory effect on the acetylcholine (ACh)-induced vasorelaxation of rat aorta with the endothelium. The quinones 3, at a low concentration of 0.1 μM, reduced the maximal response with increase of EC50 values for ACh. The results indicate that quinones 3 are potent inhibitors of endothelium-dependent vasorelaxation. © 2002 Éditions scientifiques et médicales Elsevier SAS. All rights reserved. | * |
dc.language | English | * |
dc.title | 6-Arylamino-5,8-quinazolinediones as potent inhibitors of endothelium-dependent vasorelaxation | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 37 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 77 | * |
dc.relation.lastpage | 82 | * |
dc.relation.journaltitle | European Journal of Medicinal Chemistry | * |
dc.identifier.doi | 10.1016/S0223-5234(01)01290-9 | * |
dc.identifier.wosid | WOS:000174532700008 | * |
dc.identifier.scopusid | 2-s2.0-0036176128 | * |
dc.author.google | Ryu C.-K. | * |
dc.author.google | Shin K.-H. | * |
dc.author.google | Seo J.-H. | * |
dc.author.google | Kim H.-J. | * |
dc.contributor.scopusid | 유충규(15846918400) | * |
dc.contributor.scopusid | 김화정(56670336100) | * |
dc.date.modifydate | 20240118124308 | * |