DSpace at EWHA: Structure-activity relationships of apio nucleosides as potential antiviral agents

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DC Field	Value	Language
dc.contributor.author	정낙신	-
dc.date.accessioned	2016-08-28T11:08:46Z	-
dc.date.available	2016-08-28T11:08:46Z	-
dc.date.issued	2001	-
dc.identifier.issn	1525-7770	-
dc.identifier.other	OAK-805	-
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/218850	-
dc.description.abstract	Several types of novel apio nucleosides were synthesized starting from 1,3-dihydroxyacetone and evaluated for antiviral activity. Among compounds tested, amino substituted apio dideoxynucleosides exhibited anti-HBV activity, while thioapio dideoxynucleosides were found to be active against HIV-1. Apio dideoxydidehydro nucleosides showed moderate to potent anti-HCMV activity, but their bioisosteric thioapio dideoxydidehydro nucleosides did not exhibit any significant antiviral activity.	-
dc.language	English	-
dc.title	Structure-activity relationships of apio nucleosides as potential antiviral agents	-
dc.type	Conference Paper	-
dc.relation.issue	4-7	-
dc.relation.volume	20	-
dc.relation.index	SCIE	-
dc.relation.index	SCOPUS	-
dc.relation.startpage	657	-
dc.relation.lastpage	660	-
dc.relation.journaltitle	Nucleosides, Nucleotides and Nucleic Acids	-
dc.identifier.doi	10.1081/NCN-100002344	-
dc.identifier.wosid	WOS:000170690500047	-
dc.identifier.scopusid	2-s2.0-0034839590	-
dc.author.google	Jeong L.S.	-
dc.author.google	Moon H.R.	-
dc.author.google	Hong J.H.	-
dc.author.google	Yoo S.J.	-
dc.author.google	Choi W.J.	-
dc.author.google	Kim H.O.	-
dc.author.google	Ahn H.S.	-
dc.author.google	Baek H.W.	-
dc.author.google	Chun M.W.	-
dc.author.google	Kim H.-D.	-
dc.author.google	Kim J.	-
dc.author.google	Choi J.-R.	-
dc.contributor.scopusid	정낙신(16028528200)	-
dc.date.modifydate	20211210153610	-