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Cytokine Delivery and Tissue Engineering

Title
Cytokine Delivery and Tissue Engineering
Authors
Lee S.J.
Ewha Authors
이승진
SCOPUS Author ID
이승진scopus
Issue Date
2000
Journal Title
Yonsei Medical Journal
ISSN
0513-5796JCR Link
Citation
vol. 41, no. 6, pp. 704 - 719
Indexed
SCI; SCIE; SCOPUS; KCI WOS scopus
Abstract
Tissue engineering has been applied to various tissues, and particularly significant progress has been made in the areas of skin, cartilage, and bone regeneration. Inclusion of bioactive factors into the synthetic scaffolds has been suggested as one of the possible tissue engineering strategies. The growth factors are polypeptides that transmit signals to modulate cellular activities. They have short half-lives, for example, platelet-derived growth factor (PDGF), isolated from platelets, has a half life of less than 2 minutes when injected intravenously. Extended biological activity and the controlled release of growth factor are achieved by incorporating growth factor into the polymeric device. This review will focus on growth factor delivery for tissue engineering. Particular examples will be given whereby growth factors are delivered from a tissue-engineered device to facilitate wound healing and tissue repair.
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약학대학 > 약학과 > Journal papers
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