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dc.contributor.author전길자-
dc.date.accessioned2016-08-28T11:08:18Z-
dc.date.available2016-08-28T11:08:18Z-
dc.date.issued1999-
dc.identifier.issn0918-6158-
dc.identifier.otherOAK-293-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/218559-
dc.description.abstractThe mechanism of phagocytic activity of the ethyl alcohol fraction of Cervus nippon (CN-E) was investigated in vivo. The administration of CN-E (100 mg/kg, p.o.) enhanced lucigenin chemiluminescence and the engulfment of fluorescein-conjugated E. coli particles in murine peritoneal macrophages. Phagocytic activity was suppressed by the treatment of S-nitrosoglutathione (GSNO) which is an exogenous nitric oxide donor depending on the concentration of dose. CN-E suppressed the production of nitric oxide and enhanced the concentration in [Ca2+](i). The enhancement in [Ca2+](i) was diminished by the treatment of EGTA. These results indicate that CN-E enhances the phagocytic activity of murine peritoneal macrophage via a suppression of nitric oxide production and an increase in [Ca2+](i).-
dc.languageEnglish-
dc.titlePhagocytic activity of ethyl alcohol fraction of deer antler in murine peritoneal macrophage-
dc.typeArticle-
dc.relation.issue9-
dc.relation.volume22-
dc.relation.indexSCI-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage932-
dc.relation.lastpage935-
dc.relation.journaltitleBiological and Pharmaceutical Bulletin-
dc.identifier.wosidWOS:000082660800009-
dc.identifier.scopusid2-s2.0-0032821186-
dc.author.googleSuh J.-S.-
dc.author.googleEun J.-S.-
dc.author.googleSo J.-N.-
dc.author.googleSeo J.-T.-
dc.author.googleJhon G.-J.-
dc.contributor.scopusid전길자(6701488476)-
dc.date.modifydate20180301081000-


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