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Synthesis and cytotoxic activities of 6-chloro-7-arylamino-5,8- isoquinolinediones

Title
Synthesis and cytotoxic activities of 6-chloro-7-arylamino-5,8- isoquinolinediones
Authors
Ryu C.-K.Lee I.-K.Jung S.-H.Lee C.-O.
Ewha Authors
유충규
SCOPUS Author ID
유충규scopus
Issue Date
1999
Journal Title
Bioorganic and Medicinal Chemistry Letters
ISSN
0960-894XJCR Link
Citation
vol. 9, no. 8, pp. 1075 - 1080
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
6-Chloro-7-arylamino-5,8-isoquinolinediones were newly synthesized and evaluated for in vitro cytotoxic activities against five human solid tumor cell lines. Among them, 5b, 5c and 5d exhibited potent activities against the cell lines HCT-15 and SK-MEL-2.
DOI
10.1016/S0960-894X(99)00152-3
Appears in Collections:
약학대학 > 약학과 > Journal papers
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