Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이경림 | * |
dc.date.accessioned | 2016-08-28T11:08:09Z | - |
dc.date.available | 2016-08-28T11:08:09Z | - |
dc.date.issued | 1998 | * |
dc.identifier.issn | 0253-6269 | * |
dc.identifier.other | OAK-134 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/218462 | - |
dc.description.abstract | The complete nucleotide sequence of the cDNA clone encoding rat skeletal muscle myosin-binding protein H (MyBP-H) was determined and amino acid sequence was deduced from the nucleotide sequence (GenBank accession number AF077338). The full-length cDNA of 1782 base pairs(bp) contains a single open reading frame of 1454 bp encoding a rat MyBP-H protein of the predicted molecular mass 52.7kDa and includes the common consensus 'CA_ _TG' protein binding motif. The cDNA sequence of rat MyBP-H show 92%, 84% and 41% homology with those of mouse, human and chicken, respectively. The protein contains tandem internal motifs array (-FN III-Ig C2-FN III- Ig C2-) in the C-terminal region which resembles to the immunoglobulin superfamily C2 and fibronectin type III motifs. The amino acid sequence of the C-terminal Ig C2 was highly conserved among MyBPs family and other thick filament binding proteins, suggesting that the C-terminal Ig C2 might play an important role in its function. All proteins belonging to MyBP-H member contains 'RKPS' sequence which is assumed to be cAMP- and cGMP-dependent protein kinase A phosphorylation site. Computer analysis of the primary sequence of rat MyBP-H predicted 11 protein kinase C (PKC) phosphorylation site, 7 casein kinase II (CK2) phosphorylation site and 4 N-myristoylation site. | * |
dc.language | English | * |
dc.title | Nucleotide and deduced amino acid sequences of rat myosin binding protein H (MyBP-H) | * |
dc.type | Article | * |
dc.relation.issue | 6 | * |
dc.relation.volume | 21 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 712 | * |
dc.relation.lastpage | 717 | * |
dc.relation.journaltitle | Archives of Pharmacal Research | * |
dc.identifier.wosid | WOS:000077549800017 | * |
dc.identifier.scopusid | 2-s2.0-0032240450 | * |
dc.author.google | Jung J. | * |
dc.author.google | Oh J. | * |
dc.author.google | Lee K. | * |
dc.contributor.scopusid | 이경림(7501517435) | * |
dc.date.modifydate | 20240301081003 | * |