Steroidal glycosides of the 14,15-seco-18-nor-pregnane series from Cynanchum ascyrifolium

Abstract

Three new steroidal glycosides named cynascyrosides A-C were isolated from the roots of Cynanchum ascyrifolium. The structures of these compounds were determined on the basis of spectroscopic and chemical evidence as cynajapogenin A 3-O-α-D-oleandropyranosyl-(1 → 4)-β-L-cymaropyranosyl-(1 → 4)-β-D-digitoxopyranoside; cynajapogenin A 3-O-β-D-glucopyranosyl-(1 → 4)-α-L-cymaropyranosyl-(1 → 4)-β-L-cymaropyranosyl-(1→4)-β-L- cymaropyranoside; cynajapogenin A 3-O-β-D-glucopyranosyl-(1 → 4)-α-L- cymaropyranosyl-(1 → 4)-β-D-digitoxopyranosyl-(1 → 4)-β-L- cymaropyranoside.