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dc.contributor.author정낙신-
dc.date.accessioned2017-08-28T09:36:05Z-
dc.date.available2017-08-28T09:36:05Z-
dc.date.issued1998-
dc.identifier.issn0253-6269-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/218415-
dc.description.abstract2′-Fluorohexopyranosyl nucleosides 1a and 1b which contained a bioisosteric double bond and a fluorine were synthesized in 12 steps, starting from D-galactose. During diethylaminosulfur trifluoride (DAST) fluorination, retention of stereochemistry was observed through the participation of methoxy or chloro group at the 6-position of the purine base. The final nucleosides 1a and 1b were found to be inactive against HIV-1 and HSV-1,2.-
dc.languageEnglish-
dc.titleSynthesis and antiviral activity of 2′-fluorohexopyranosyl nucleosides-
dc.typeArticle-
dc.relation.issue3-
dc.relation.volume21-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage338-
dc.relation.lastpage343-
dc.relation.journaltitleArchives of Pharmacal Research-
dc.identifier.wosidWOS:000074151900020-
dc.identifier.scopusid2-s2.0-0032082743-
dc.author.googleJeong L.S.-
dc.author.googleLee J.E.-
dc.author.googleKim H.O.-
dc.author.googleChun M.W.-
dc.date.modifydate20160429000000-
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약학대학 > 약학과 > Journal papers
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