Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이공주 | - |
dc.date.accessioned | 2016-08-28T11:08:03Z | - |
dc.date.available | 2016-08-28T11:08:03Z | - |
dc.date.issued | 1998 | - |
dc.identifier.issn | 0014-5793 | - |
dc.identifier.other | OAK-12 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/218397 | - |
dc.description.abstract | The transactivation potential of Nm23-H1, a homolog of c-myc transcription factor Nm23-H2/PuF was assessed in yeast as a fusion protein with the DNA binding domains (DBDs) of GAL4 and LexA. The C-terminal half of Nm23-H1 exhibited strong transactivation of the reporter genes, LacZ and Leu2 carrying GAL4 and LexA upstream activating sequences (UASs), whereas the full-length Nm23-H1 and its N-terminal did not. Similar results were also obtained with Nm23-H2/PuF transactivating the reporter genes only by the C- terminus fused to GAL4 and LexA DBDs. Hence, our results suggested a possible regulatory role of the N-termini of Nm23 isotypes upon transactivation. | - |
dc.language | English | - |
dc.title | Transactivation potential of the C-terminus of human Nm23-H1 | - |
dc.type | Article | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 423 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 235 | - |
dc.relation.lastpage | 238 | - |
dc.relation.journaltitle | FEBS Letters | - |
dc.identifier.doi | 10.1016/S0014-5793(98)00100-8 | - |
dc.identifier.wosid | WOS:000072282000024 | - |
dc.identifier.scopusid | 2-s2.0-0032548787 | - |
dc.author.google | Chae S.-K. | - |
dc.author.google | Lee N.-S. | - |
dc.author.google | Lee K.-J. | - |
dc.author.google | Kim E. | - |
dc.contributor.scopusid | 이공주(7501497635;57191532162) | - |
dc.date.modifydate | 20230208115507 | - |