Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤주영 | * |
dc.contributor.author | 남상집 | * |
dc.date.accessioned | 2016-08-28T11:08:57Z | - |
dc.date.available | 2016-08-28T11:08:57Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 0003-2700 | * |
dc.identifier.issn | 1520-6882 | * |
dc.identifier.other | OAK-18963 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/218348 | - |
dc.description.abstract | Hypochlorite (OCl-) plays a key role in the immune system and is involved in various diseases. Accordingly, direct detection of endogenous OCl- at the subcellular level is important for understanding inflammation and cellular apoptosis. In the current study, a two-photon fluorescent off/on probe (PNIS) bearing imidazoline-2-thione as an OCl- recognition unit and triphenylphosphine (TPP) as a mitochondrial-targeting group was synthesized and examined for its ability to image mitochondrial OCl- in situ. This probe, based on the specific reaction between imidazoline-2-thione and OCl-, displayed a selective fluorescent off/on response to OCl- with the various reactive oxygen species in a physiological medium. PNIS was successfully applied to image of endogenously produced mitochondrial OCl- in live RAW 264.7 cells-via two-photon microscopy. | * |
dc.language | English | * |
dc.publisher | AMER CHEMICAL SOC | * |
dc.title | A Selective Imidazoline-2-thione-Bearing Two-Photon Fluorescent Probe for Hypochlorous Acid in Mitochondria | * |
dc.type | Article | * |
dc.relation.issue | 12 | * |
dc.relation.volume | 88 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 6615 | * |
dc.relation.lastpage | 6620 | * |
dc.relation.journaltitle | ANALYTICAL CHEMISTRY | * |
dc.identifier.doi | 10.1021/acs.analchem.6b01738 | * |
dc.identifier.wosid | WOS:000378470200073 | * |
dc.identifier.scopusid | 2-s2.0-84975865209 | * |
dc.author.google | Xu, Qingling | * |
dc.author.google | Heo, Cheol Ho | * |
dc.author.google | Kim, Jin A. | * |
dc.author.google | Lee, Hye Sue | * |
dc.author.google | Hu, Ying | * |
dc.author.google | Kim, Dayoung | * |
dc.author.google | Swamy, Kunemadihalli Mathada Kotraiah | * |
dc.author.google | Kim, Gyoungmi | * |
dc.author.google | Nam, Sang-Jip | * |
dc.author.google | Kim, Hwan Myung | * |
dc.author.google | Yoon, Juyoung | * |
dc.contributor.scopusid | 윤주영(7403587371) | * |
dc.contributor.scopusid | 남상집(57208839798) | * |
dc.date.modifydate | 20240220120010 | * |