Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 류재상 | * |
dc.date.accessioned | 2016-08-27T04:08:26Z | - |
dc.date.available | 2016-08-27T04:08:26Z | - |
dc.date.issued | 2015 | * |
dc.identifier.issn | 0968-0896 | * |
dc.identifier.issn | 1464-3391 | * |
dc.identifier.other | OAK-15912 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/217762 | - |
dc.description.abstract | The synthesis of tubulysin analogs containing stereochemically diverse cyclic Tuv moieties is described. A tetrahydropyranyl moiety was incorporated into the Tuv unit by enantioselective hetero Diels-Alder reactions of Danishefsky's diene and thiazole aldehyde. Four different stereoisomers of cyclic Tuv units were used as surrogates for the Tuv moiety. The synthesized stereochemically diverse simplified cyclic analogs were evaluated for the inhibition of tubulin polymerization. (C) 2015 Elsevier Ltd. All rights reserved. | * |
dc.language | English | * |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | * |
dc.subject | Tubulysin | * |
dc.subject | Antitumor agents | * |
dc.subject | Peptides | * |
dc.subject | Asymmetric catalysis | * |
dc.subject | Hetero Diels-Alder reaction | * |
dc.title | Synthesis of stereochemically diverse cyclic analogs of tubulysins | * |
dc.type | Article | * |
dc.relation.issue | 21 | * |
dc.relation.volume | 23 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 6827 | * |
dc.relation.lastpage | 6843 | * |
dc.relation.journaltitle | BIOORGANIC & MEDICINAL CHEMISTRY | * |
dc.identifier.doi | 10.1016/j.bmc.2015.10.003 | * |
dc.identifier.wosid | WOS:000364437400006 | * |
dc.identifier.scopusid | 2-s2.0-84946110449 | * |
dc.author.google | Park, Yunjeong | * |
dc.author.google | Bae, Song Yi | * |
dc.author.google | Hah, Jung-Mi | * |
dc.author.google | Lee, Sang Kook | * |
dc.author.google | Ryu, Jae-Sang | * |
dc.contributor.scopusid | 류재상(36081118200) | * |
dc.date.modifydate | 20231120165709 | * |