Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 남상집 | * |
dc.date.accessioned | 2016-08-27T04:08:02Z | - |
dc.date.available | 2016-08-27T04:08:02Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 0253-6269 | * |
dc.identifier.issn | 1976-3786 | * |
dc.identifier.other | OAK-15531 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/217545 | - |
dc.description.abstract | Natural products are a major pipeline for drug development and are responsible for more than 50 % of drugs on the market. NMR is a fundamental and powerful tool for the structure determination of natural products. It is essential to provide unambiguous chemical structure information on natural products in drug development research, including the structure-activity relationship, derivatization and pharmacokinetic/pharmacodynamic studies. Advancement of NMR instruments has made it possible to deal with nanomole-scale natural products for structure elucidation, but misinterpretation of NMR spectra still occurs. We review 21 natural products with revised chemical structures and the methods used for those revisions. | * |
dc.language | English | * |
dc.publisher | PHARMACEUTICAL SOC KOREA | * |
dc.subject | Natural product | * |
dc.subject | NMR | * |
dc.subject | Structure determination | * |
dc.subject | Structure-activity relationship | * |
dc.subject | Drug development | * |
dc.subject | PK/PD | * |
dc.title | Misassigned natural products and their revised structures | * |
dc.type | Review | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 39 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 143 | * |
dc.relation.lastpage | 153 | * |
dc.relation.journaltitle | ARCHIVES OF PHARMACAL RESEARCH | * |
dc.identifier.doi | 10.1007/s12272-015-0649-9 | * |
dc.identifier.wosid | WOS:000370263600001 | * |
dc.identifier.scopusid | 2-s2.0-84958117108 | * |
dc.author.google | Yoo, Hye-Dong | * |
dc.author.google | Nam, Sang-Jip | * |
dc.author.google | Chin, Young-Won | * |
dc.author.google | Kim, Min-Sun | * |
dc.contributor.scopusid | 남상집(57208839798) | * |
dc.date.modifydate | 20240220120010 | * |