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Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages

Title
Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages
Authors
Kwon, JaeyoungBasnet, SunitaLee, Jin WooSeo, Eun-KyoungTsevegsuren, NanzadHwang, Bang YeonLee, Dongho
Ewha Authors
서은경
SCOPUS Author ID
서은경scopus
Issue Date
2015
Journal Title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN
0960-894XJCR Link1464-3405JCR Link
Citation
vol. 25, no. 16, pp. 3314 - 3318
Keywords
Sophora alopecuroides L.FlavonostilbenesNitric oxide production inhibitor
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Three new flavonostilbenes, alopecurones M-O (1-3), were isolated from the root bark of Sophora alopecuroides L. together with 21 known compounds. The structures of the isolated compounds were elucidated by using NMR, MS, and CD spectroscopic data. All isolates were evaluated for their potential to inhibit LPS-induced nitric oxide production in RAW 264.7 cells. (C) 2015 Elsevier Ltd. All rights reserved.
DOI
10.1016/j.bmcl.2015.05.062
Appears in Collections:
약학대학 > 약학과 > Journal papers
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