Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이윤실 | * |
dc.date.accessioned | 2016-08-27T04:08:15Z | - |
dc.date.available | 2016-08-27T04:08:15Z | - |
dc.date.issued | 2015 | * |
dc.identifier.issn | 1226-4512 | * |
dc.identifier.issn | 2093-3827 | * |
dc.identifier.other | OAK-14643 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/217058 | - |
dc.description.abstract | The aim of the present study was to assess whether exposure to the combination of an extremely low frequency magnetic field (ELF-MF; 60 Hz, 1 mT or 2 mT) with a stress factor, such as ionizing radiation (IR) or H2O2, results in genomic instability in non-tumorigenic human lung epithelial L132 cells. To this end, the percentages of G2/M-arrested cells and aneuploid cells were examined. Exposure to 0.5 Gy IR or 0.05 mM H2O2 for 9 h resulted in the highest levels of aneuploidy; however, no cells were observed in the subG1 phase, which indicated the absence of apoptotic cell death. Exposure to an ELF-MF alone (1 mT or 2 mT) did not affect the percentages of G2/M-arrested cells, aneuploid cells, or the populations of cells in the subG1 phase. Moreover, when cells were exposed to a 1 mT or 2 mT ELF-MF in combination with IR (0.5 Gy) or H2O2 (0.05 mM), the ELF-MF did not further increase the percentages of G2/M-arrested cells or aneuploid cells. These results suggest that ELF-MFs alone do not induce either G2/M arrest or aneuploidy, even when administered in combination with different stressors. | * |
dc.language | English | * |
dc.publisher | KOREAN JOURNAL OF PHYSIOLOGY & | * |
dc.publisher | PHARMACOLOGY | * |
dc.subject | Aneuploidy | * |
dc.subject | Extremely low frequency | * |
dc.subject | G2/M phase | * |
dc.subject | H2O2 | * |
dc.subject | Ionizing radiation | * |
dc.title | Effects on G2/M Phase Cell Cycle Distribution and Aneuploidy Formation of Exposure to a 60 Hz Electromagnetic Field in Combination with Ionizing Radiation or Hydrogen Peroxide in L132 Nontumorigenic Human Lung Epithelial Cells | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 19 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 119 | * |
dc.relation.lastpage | 124 | * |
dc.relation.journaltitle | KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY | * |
dc.identifier.doi | 10.4196/kjpp.2015.19.2.119 | * |
dc.identifier.wosid | WOS:000350613600006 | * |
dc.author.google | Jin, Hee | * |
dc.author.google | Yoon, Hye Eun | * |
dc.author.google | Lee, Jae-Seon | * |
dc.author.google | Kim, Jae-Kyung | * |
dc.author.google | Myung, Sung Ho | * |
dc.author.google | Lee, Yun-Sil | * |
dc.contributor.scopusid | 이윤실(17137192000) | * |
dc.date.modifydate | 20240130115944 | * |